Terapi Plasma Konvalesen untuk Pasien Covid-19, Menjanjikan atau Tidak Bermanfaat?

Referensi

Agarwal Anup, dkk., 2020. Convalescent plasma in the management of moderate covid-19 in adults in India: open label phase II multicentre randomised controlled trial (PLACID Trial) BMJ 2020; 371 :m3939

Romina Libster, dkk., 2021. Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults. DOI: 10.1056/NEJMoa2033700

Ventura A. Simonovich, dkk., 2020. A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia. DOI: 10.1056/NEJMoa2031304

Rajendran K, Krishnasamy N, Rangarajan J, Rathinam J, Natarajan M, Ramachandran A. Convalescent plasma transfusion for the treatment of COVID-19: Systematic review. J Med Virol. 2020;92(9):1475-1483. doi:10.1002/jmv.25961 

Wenjing L, Yuanzheng F, Li JY, Tang LV, Yu H. Safety and efficacy of convalescent plasma therapy in severely and critically ill patients with COVID-19: a systematic review with meta-analysis. Aging (Albany NY). 2020 Dec 15;13(1):1498-1509. doi: 10.18632/aging.202195. Epub 2020 Dec 15. PMID: 33323550; PMCID: PMC7835046. 

Meher BR, Padhy BM, Das S, Mohanty RR, Agrawal K. Effectiveness of Convalescent Plasma Therapy in the Treatment of Moderate to Severe COVID 19 Patients: A Systematic Review and Meta-Analysis. J Assoc Physicians India. 2020 Dec;68(12):35-43. PMID: 33247641. 

Szakó, L., Farkas, N., Kiss, S. et al. Convalescent plasma therapy for COVID-19 patients: a protocol of a prospective meta-analysis of randomized controlled trials. Trials 22, 112 (2021). https://doi.org/10.1186/s13063-021-05066-2